Evaluation of volume-weighted mean nuclear volume in endometrial lesions.

نویسندگان

  • E Artacho-Pérula
  • R Roldán-Villalobos
چکیده

The individual nuclear size was studied in three groups of endometrial samples (simple hyperplasia -SH-, atypical hyperplasia -AH-, and well-differentiated adenocarcinoma -WDA-). The application of recent semiquantitative systems in combination with stereological methods permits a simple, quick and unbiased estimation of the volume-weighted mean nuclear volume vv(nucl). We have found an increase in the vv(nucl) from SH to AH to WDA. There are significant differences between the mean of the three groups (p < 0.01). The variance associated with estimates of vv(nucl) is mainly provided by differences among lesions; i.e. patients. This capacity for discriminating may be associated with gland and lumen endometrial quantification to improve the correct diagnosis of endometrial samples.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Stereological Study on the Neurons of Superior Cervical Sympathetic Ganglion in Diabetic Rats

Background: Most research on autonomic dysfunction of diabetes mellitus is conducted on ganglions innervating gastrointestinal (GI) tract and there are limited works focusing on cervical sympathetic ganglia. The effects of diabetes mellitus (DM) on the neurons of superior cervical sympathetic ganglion (SCSG) are investigated by stereological methods. Material and Methods: Female rats (n=72) ran...

متن کامل

O-34: Assessment of Endometrial Volume by Four-Dimensional Ultrasound As A Predictor of Pregnancy Outcome in IVF Patient Who Refer to Royan Institute

Background: To investigate whether endometrial volume on the day of HCG (human chorionic gonadotropin) administration is a predictor of ART (assisted reproductive outcome) outcome Materials and Methods: Two hundred and seven patients in ART cycle were included in this prospective study; In order to evaluate endometrial volume and its relationship to ART outcome. Endometrial volume obtained from...

متن کامل

Stereologic estimation of volume-weighted mean nuclear volume as a predictor of prognosis in "thin" malignant melanoma.

At present, tumor invasion represents the most reliable prognostic factor for primary malignant melanoma. The 10-year survival rate of "thin" melanomas (Breslow less than 0.76 mm) is more than 95%, but approximately 5% of these low-risk tumors do metastasize. In an attempt to determine prognostic markers for "thin" melanomas we investigated the volume-weighted mean nuclear volume (Vv) of primar...

متن کامل

Diagnostic Pathology Research Reproducibility determination of WHO classification of endometrial hyperplasia/well differentiated adenocarcinoma and comparison with computerized morphometric data in curettage specimens in Iran

Background: Management of endometrial precancerous lesions has been of much debate due to inconsistencies in their classification, natural history and histologic diagnosis. Endometrial hyperplasia constitutes a wide range of histomorphologic features associated with high intra and interobserver diagnostic variability. Although traditional microscopic diagnosis is by far the most applicable meth...

متن کامل

Onm-1: Imaging in Female Infertility

The role of imaging in female infertility has undergone a revolution over the past few decades .Sonography plays an integral role in the evaluation of gynecologic disease. It can determine the organ or site of abnormality and provide a diagnosis or short differential in the vast majority of patients. Both the transabdominal and transvaginal approaches are now well –established techniques for as...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Histology and histopathology

دوره 8 3  شماره 

صفحات  -

تاریخ انتشار 1993